Glycinamide hydrochloride
Glycinamide hydrochloride
CAS: 1668-10-6
Molecular Formula: C2H7ClN2O
Glycinamide hydrochloride - Names and Identifiers
| Name | Glycinamide hydrochloride |
| Synonyms | H-Gly-NH2·HCl H-GLY-NH2 HCL GLYCINE-NH2 HCL GLYCINAMIDE HCI Glycinamide HCL Glycinamide hydrochl GLY-NH2 HYDROCHLORIDE 2-amino-2-oxoethanaminium Glycinamide hydrochloride GLYCINE AMIDE HYDROCHLORIDE Aminoacetamide hydrochloride Glycinamide monohydrochloride 2-AMINOACETAMIDE HYDROCHLORIDE Acetamide, 2-amino-, monohydrochloride GLYCINAMIDEHYDROCHLORIDE,BIOLOGICALBUFFER |
| CAS | 1668-10-6 |
| EINECS | 216-789-1 |
| InChI | InChI=1/C2H6N2O/c3-1-2(4)5/h1,3H2,(H2,4,5)/p+1 |
| InChIKey | WKNMKGVLOWGGOU-UHFFFAOYSA-N |
Glycinamide hydrochloride - Physico-chemical Properties
| Molecular Formula | C2H7ClN2O |
| Molar Mass | 110.54 |
| Melting Point | 204°C (dec.)(lit.) |
| Boling Point | 281.3°C at 760 mmHg |
| Flash Point | 123.9°C |
| Water Solubility | Soluble in water (1100g/L). |
| Solubility | H2O: 0.1g/mL, clear |
| Vapor Presure | 0.00359mmHg at 25°C |
| Appearance | White to white-like solid |
| Color | White to beige |
| Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.1'] |
| BRN | 3554199 |
| pKa | 8.20(at 20℃) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| Sensitive | Hygroscopic |
| MDL | MFCD00013008 |
| Use | Used as pharmaceutical intermediates for organic synthesis |
Glycinamide hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29241900 |
| Hazard Class | IRRITANT |
Glycinamide hydrochloride - Introduction
Easily soluble in water, slightly soluble in alcohol.
Last Update：2022-10-16 17:14:17
Glycinamide hydrochloride - Reference Information
| use | used as a pharmaceutical intermediate for organic synthesis the product is cyclized with glyoxal to obtain 2-hydroxypyrazine, and 2, 3-dichloropyrazine can be produced by chlorination with phosphorus oxychloride for the production of sulfa drug SMPZ. Used as buffer in the physiological pH range. Buffer; for peptide coupling |
| Production method | is obtained by amination of methyl chloroacetate. The ammonia water is cooled to below 0 ℃, and methyl chloroacetate is added dropwise, and the temperature is kept for 2 hours. Ammonia is passed to a predetermined amount below 20 ℃, and after standing for 8 hours, the residual ammonia is removed, the temperature is raised to 60 ℃, and concentrated under reduced pressure to obtain aminoacetamide hydrochloride. |
Last Update：2024-04-09 20:49:11
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